In the current review article novel discovery of traditional plants and herbal products are gaining famous in the scientific community present days owing to their reliable pharmacological properties and affordability to prices for the common people which develops them efficacy in control of various diseases. They have made significant contributions to rural livelihoods, and many, in addition to traditional healers who practice herbal medicine People are involved in collecting and trading medicinal plants. Thus, the global demand for herbal medicines has increased, which has led to the realization of advanced new medicines. Most communities in developing countries are deeply involved in the use of medicinal plants due to the alarming poverty rates, so this requires scientific support, especially in reducing their effectiveness in treating such diseases. In their pure compounds or standardized plant extracts, they offer unlimited opportunities for new drugs because they cannot compensate for their chemical diversity. The key of natural products is associated to the efficacy of different phytochemicals such as tannins, terpenoids, cardiac glycosides, flavonoids, saponins and alkaloids are treat as cancer activity. The available reports on the phytochemicals within the general herbal plants are discussed in this review.